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Research interest
The main subjects of our work are the mechanisms of intestinal inflammation with special emphasis on T cells and myeloid cells but also the epithelial barrier. Since the founding of the group, we have a special interest in the role of the adipose tissue in the pathogenesis of chronic intestinal inflammation and its impact on the mucosal immune system. Additionally, we are interested in the immune evasion of tumors regarding the regulatory function of myeloid cells as well as CD8+ T cell activation.
Both subjects are investigated regarding the metabolic changes in the local microenvironment and epigenetic regulation of the respective cells via histone deacetylases.
Head
Director Medical Center for Gastroenterology, Infectiology and Rheumatology
CBF: Campus Benjamin Franklin
News
03.03.2025 We welcome a new member of our team
Chen Ni joins the lab as guest scientist for 12 months.
04.02.2025 Publication accepted
(Cooperation with the AG Forslund from the MDC)
"Mucosal washes are useful for sampling intestinal mucus-associated microbiota despite low biomass"
Gut Microbes
22.11.2024 Collaborative Research Center (SFB) 1449 "Dynamic Hydrogels at Biointerfaces" extendend
- Projekt "Hydrogel properties on intestinal surfaces in health and disease" in collaboration with AG Weinhart (FU Berlin)
- Core unit: "In vitro and in vivo hydrogel model systems core unit" in collaboration with AG Weinhart and AG Duerr (BIH)
